Development of Sunscreen Cream from Riceberry Extract

Abstract

Riceberry (Oryza sativa) is rich in various vitamins and contains an important substance called anthocyanin, which is a highly effective antioxidant. It can inhibit skin damage caused by the oxidative process triggered by ultraviolet light. This research investigated the biological activities of riceberry extract (OSE) and developed a sunscreen formula incorporating this extract. The study assessed the inhibition of tyrosinase enzyme production in melanoma cells (B16F10) and evaluated the properties and stability of the product under accelerated conditions. It was determined that riceberry extract (OSE) at concentrations ranging from 0.0001 to 1 mg/ml was non-toxic to B16F10 cells. At a concentration of 1 mg/ml, riceberry extract (OSE) inhibited melanin production in B16F10 cells by 20.60±3.67% but did not affect the production of the tyrosinase enzyme when compared to kojic acid. Additionally, among six tested sunscreen formulas, the fifth formula proved to be the most stable under accelerated conditions.