Antimicrobial activity of Amomum krervanh seed extract against Escherichia coli and Staphylococcus aureus

Abstract

The purpose of this of this study was to evaluate the antimicrobial activities of Amomum krervanh seed extract against two bacterial pathogens, Escherichia coli and Staphylococcus aureus. The disc diffusion method was employed to measure the inhibition zones produced by the seed extract. The extract exhibited its largest inhibition zone with an average diameter of 7.33 ± 0.6 mm. Comparative analysis was conducted using standard antimicrobial agents, including the antibiotics Amikacin, Ampicillin, and Clotrimazole. The results demonstrated that the inhibition zones produced by A. krervanh seed extract were smaller than those of Amikacin and Ampicillin, indicating lower antibacterial efficacy compared to these antibiotics. However, the extract outperformed Clotrimazole, showing a larger inhibition zone, particularly against E. coli. This finding highlights the extract’s relatively stronger antimicrobial potential in this context. Additionally, the study found that the extract was more effective against E. coli than against S. aureus when compared to Clotrimazole. These findings indicate that A. krervanh seed extract possesses significant antimicrobial properties, particularly in inhibiting the growth of E. coli and S. aureus. The extract’s effectiveness suggests its potential as a natural antimicrobial agent for developing alternative treatments or products to manage bacterial infections. The extract’s demonstrated effectiveness highlights its potential as a natural antimicrobial agent, offering opportunities to develop alternative treatments or products for managing bacterial infections. This makes it a promising candidate for innovative antimicrobial solutions to control infections and combat antibiotic resistance in the future.